V = Maximum (or limiting) velocity; MichaelisMenten constant 'KM' Since Vmax cannot be reached at any substrate concentration (because of its asymptotic behaviour, V keeps growing at any S, albeit ever more slowly), enzymes are usually characterized by the substrate concentration at which the rate of reaction is half its maximum This substrate concentration is called the MichaelisMenten constant (KMAnd Km = Michaelis constant The MME assumes that rapid equilibrium is reached among the enzyme, its substrate and the enzymesubstrate complex
Lesson 6 Michaelis Menten Kinetics Objective